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Endo TAVI

An integrated and computational environment for the analysis of markers of endothelial dysfunction, multi-detector computed tomography transthoracic echocardiography and advanced functional imaging following aortic valve replacement with transcatheter technology (TAVR) and conventional surgery (SAVR)

Progetto finanziato a valere sul P.O.C. FESR SICILIA 2014/2020, Azione 1.1.1

THE PROJECT

EndoTAVI at glance:

  • EndoTAVI stands form ‘endothelial function’ and ‘transcatheter aortic valve implantation’ / ‘replacement’ (TAVI / TAVR)
  • The EndoTAVI project aims to create an integrated environment to investigate micro- and macromarkers of early endothelial and structural prosthesis dysfunction following aortic valve replacement with surgical and transcatheter prostheses in patients affected by severe aortic valve stenosis.
  • Aortic valve stenosis is the most common heart valve disease worldwide, and aortic valve replacement is the gold standard of treatment. However, the durability of prosthetic valves and host-prosthesis interactions remains an important issue.
  • Hence, the aim of the EndoTAVI project is to generate a computational and hybrid environment to detect and diagnose early markers of surgical and transcatheter prosthesis dysfunction at the central (i.e. the aortic root) and peripheral levels (i.e. brachial artery), with the aid of advanced imaging.

Who we are

Proponents

GVM Care&Research

Principal Investigators (PIs):

Vincenzo Pernice MD

I.E.ME.S.T. - Istituto Euromediterraneo di Scienza e Tecnologia

Co-PIs:

Prof. Francesco Cappello

K2 Innovazione S.r.l.

Software Engineer:

S.E. Marco Spadaro

Intent S.r.l. Integration Management

Project managers:

Ing. Salvatore Mammoliti

Università degli Studi di Palermo

CO-PI:

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WHERE

Dipartimento di Chirurgia Cardio-Toraco-Vascolare, GVM Care&Research Maria Eleonora Hospital,

Viale della Regione Siciliana 1571,
90135 - Palermo, Italy

Istituto Euro-Medirerraneo di Scienza e Tecnologia, IEMEST

Via Michele Miraglia 20,
90139 - Palermo, Italy

K2 Innovazione srl

P.zza Ing. Panvini, 2,
94100 - Enna, Italy

Intent srl

Via Nunzio Nasi 51,
93010 - Milena (CL), Italy

CONTACT US

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